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Article

Risk estimates for complex disorders: comparing personal genome testing and family history.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Mar 2014

Aiyar Lila, Shuman Cheryl, Hayeems Robin, Dupuis Annie, Pu Shuye, Wodak Shoshana, Chitayat David, Velsher Lea, Davies Jill

Abstract excerpt

PURPOSE: Personal genome testing allows the identification of single-nucleotide polymorphisms associated with an increased risk for common complex disorders. An area of concern in the use of personal genome testing is how risk estimates generated differ from traditional measures of risk (e.g., family history analysis). We sought to analyze the concordance of risk estimates generated by family history analysis and...

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Identifiers

PMID: 24009002
DOI: 10.1038/gim.2013.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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