Article
Understanding telomere diseases through analysis of patient-derived iPS cells.
Current opinion in genetics & development - 1 Oct 2013
Batista Luis F Z, Artandi Steven E
Abstract excerpt
A unique characteristic of tissue stem cells is the ability to self-renew, a process that enables the life-long maintenance of many organs. Stem cell self-renewal is dependent in part on the synthesis of telomere repeats by the enzyme telomerase. Defects in telomerase and in genes in the telomere...
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