Article
DIST: direct imputation of summary statistics for unmeasured SNPs.
Bioinformatics (Oxford, England) - 15 Nov 2013
Lee Donghyung, Bigdeli T Bernard, Riley Brien P, Fanous Ayman H, Bacanu Silviu-Alin
Abstract excerpt
MOTIVATION: Genotype imputation methods are used to enhance the resolution of genome-wide association studies, and thus increase the detection rate for genetic signals. Although most studies report all univariate summary statistics, many of them limit the access to subject-level genotypes. Because such an access is required by all genotype imputation methods, it is helpful to develop methods that impute summary...
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