Article
Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma.
Journal of translational medicine - 29 Aug 2013
Colombino Maria, Lissia Amelia, Capone Mariaelena, De Giorgi Vincenzo, Massi Daniela, Stanganelli Ignazio, Fonsatti Ester, Maio Michele, Botti Gerardo, Caracò Corrado, Mozzillo Nicola, Ascierto Paolo A, Cossu Antonio, Palmieri Giuseppe
Abstract excerpt
BACKGROUND: Prevalence and distribution of pathogenetic mutations in BRAF and NRAS genes were evaluated in multiple melanoma lesions from patients with different geographical origin within the same Italian population. METHODS: Genomic DNA from a total of 749 tumor samples (451 primary tumors and...
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