Article
Absence of strong linkage disequilibrium between odorant receptor alleles and the major histocompatibility complex.
Human immunology - 1 Dec 2013
da Silva José Samuel, Wowk Pryscilla Fanini, Poerner Fabiana, Santos Pablo Sandro Carvalho, Bicalho Maria da Graça
Abstract excerpt
The odorant receptor (OR) genes constitute the largest gene family among vertebrates. While over 800 loci are present in the human genome, their allele diversity is still poorly characterized. It has been hypothesized that the products of OR genes can be relevant in the reproductive context, thereby interacting with products of genes of the major histocompatibility complex (MHC). Here we investigated the genetic...
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