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Sperm DNA fragmentation testing in clinical management of reproductive medicine

1 Jan 2023

Abstract excerpt

Background: Approximately 8%-12% of couples worldwide face infertility, with infertility of individuals assigned male at birth (AMAB) contributing to at least 50% of cases. Conventional semen analysis commonly used to detect sperm abnormalities is insufficient, as 30% of AMAB patients experiencing infertility show normal results in this test. From a genetic perspective, the assessment of sperm DNA fragmentation...

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PMID: 37915974
DOI: 10.1002/rmb2.12547

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