Article
Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.
Biochimica et biophysica acta - 1 Dec 2013
Dietrich Denise, Seiler Florian, Essmann Frank, Dodt Gabriele
Abstract excerpt
The attachment of organelles to the cytoskeleton and directed organelle transport is essential for cellular morphology and function. In contrast to other cell organelles like the endoplasmic reticulum or the Golgi apparatus, peroxisomes are evenly distributed in the cytoplasm, which is achieved by binding of peroxisomes to microtubules and their bidirectional transport by the microtubule motor proteins kinesin-1...
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