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Article

XRCC3 Thr241Met polymorphism and clinical outcomes of NSCLC patients receiving platinum-based chemotherapy: a systematic review and meta-analysis.

PloS one - 1 Jan 2013

Shen Xiao-yong, Lu Fan-zhen, Wu Yun, Zhao Li-ting, Lin Zhi-feng

Abstract excerpt

INTRODUCTION: X-ray repair cross-complementing protein 3 (XRCC3) is an essential gene involved in the double-strand break repair pathway. Published evidence has shown controversial results about the relationship between XRCC3 Thr241Met polymorphism and clinical outcomes of non-small cell lung cancer (NSCLC) patients receiving platinum-based chemotherapy. METHODS: A systematic review and meta-analysis was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23940523
DOI: 10.1371/journal.pone.0069553
PMCID: PMC3734199

Genes

XRCC3

Provenance

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XRCC3 Thr241Met polymorphism and clinical outcomes of NSCLC patients receiving platinum-based chemotherapy: a systematic review and meta-analysis.PMID 23940523Read ↗

XRCC3 Thr241Met is associated with response to platinum-based chemotherapy but not survival in advanced non-small cell lung cancer.Semantic proximity Read ↗

Predictive effect of XRCC3 Thr241Met polymorphism on platinum-based chemotherapy in lung cancer patients: meta-analysis.Semantic proximity Read ↗

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