Article
Genetic variations in the beta-tubulin gene and the internal transcribed spacer 2 region of Trichuris species from man and baboons.
Parasites & vectors - 12 Aug 2013
Hansen Tina V A, Thamsborg Stig M, Olsen Annette, Prichard Roger K, Nejsum Peter
Abstract excerpt
BACKGROUND: The whipworm Trichuris trichiura has been estimated to infect 604 - 795 million people worldwide. The current control strategy against trichuriasis using the benzimidazoles (BZs) albendazole (400 mg) or mebendazole (500 mg) as single-dose treatment is not satisfactory. The occurrence of single nucleotide polymorphisms (SNPs) in codons 167, 198 or 200 of the beta-tubulin gene has been reported to...
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