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Article

Preclinical evaluation of 4-methylthiobutyl isothiocyanate on liver cancer and cancer stem cells with different p53 status.

PloS one - 1 Jan 2013

Lamy Evelyn, Hertrampf Anke, Herz Corinna, Schüler Julia, Erlacher Miriam, Bertele Daniela, Bakare Adekunle, Wagner Meike, Weiland Timo, Lauer Ulrich, Drognitz Oliver, Huber Roman, Rohn Sascha, Giesemann Torsten, Mersch-Sundermann Volker

Abstract excerpt

Isothiocyanates from plants of the order Brassicales are considered promising cancer chemotherapeutic phytochemicals. However, their selective cytotoxicity on liver cancer has been barely researched. Therefore, in the present study, we systematically studied the chemotherapeutic potency of 4-meth...

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Identifiers

PMID: 23936472
DOI: 10.1371/journal.pone.0070846
PMCID: PMC3732292

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23936472-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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