Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genistein Inhibits Prostate Cancer Cell Growth by Targeting miR-34a and Oncogenic HOTAIR

1 Aug 2013

Abstract excerpt

OBJECTIVE: Genistein is a soy isoflavone that has antitumor activity both in vitro and in vivo. It has been shown that genistein inhibits many type of cancers including prostate cancer (PCa) by regulating several cell signaling pathways and microRNAs (miRNAs). Recent studies suggest that the long non-coding RNAs (lncRNAs) are also involved in many cellular processes. At present there are no reports about the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Phytoestrogen effects and research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23936419
DOI: 10.1371/journal.pone.0070372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genistein Inhibits Prostate Cancer Cell Growth by Targeting miR-34a and Oncogenic HOTAIRPMID 23936419Read ↗

Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151Semantic proximity Read ↗

Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cellsSemantic proximity Read ↗

Genistein as a regulator of signaling pathways and microRNAs in different types of cancersSemantic proximity Read ↗

Knockdown of the long noncoding RNA HOTTIP inhibits cell proliferation and enhances cell sensitivity to cisplatin by suppressing the Wnt/β‐catenin pathway in prostate cancerSemantic proximity Read ↗

Genetic and epigenetic regulations of prostate cancer by genisteinSemantic proximity Read ↗

Effects of genistein supplementation on genome-wide DNA methylation and gene expression in patients with localized prostate cancerSemantic proximity Read ↗

Flavonoids as Epigenetic Modulators for Prostate Cancer PreventionSemantic proximity Read ↗

Soy‐derived isoflavones as chemo‐preventive agents targeting multiple signalling pathways for cancer prevention and therapySemantic proximity Read ↗

Genistein treatment duration effects biomarkers of cell motility in human prostateSemantic proximity Read ↗

Tazarotene-Induced Gene 1 (TIG1) Expression in Prostate Carcinomas and Its Relationship to TumorigenicitySemantic proximity Read ↗

miR-377 inhibits the tumorous behavior of prostate cancer cells by targeting MYCSemantic proximity Read ↗

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.