Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151

23 Aug 2012

Abstract excerpt

Genistein has been shown to suppress the growth of several cancers through modulation of various pathways. However, the effects of genistein on the regulation of oncogenic microRNA-151 (miR-151) have not been reported. In this study, we investigated whether genistein could alter the expression of oncogenic miR-151 and its target genes that are involved in the progression and metastasis of prostate cancer (PCa)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation
Share to Phytoestrogen effects and research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22928040
DOI: 10.1371/journal.pone.0043812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151PMID 22928040Read ↗

Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cellsSemantic proximity Read ↗

Genistein Inhibits Prostate Cancer Cell Growth by Targeting miR-34a and Oncogenic HOTAIRSemantic proximity Read ↗

Overexpressed MicroRNA-182 Promotes Proliferation and Invasion in Prostate Cancer PC-3 Cells by Down-Regulating N-myc Downstream Regulated Gene 1 (NDRG1)Semantic proximity Read ↗

Inhibition of miR-423-5p suppressed prostate cancer through targeting GRIM-19Semantic proximity Read ↗

Genistein as a regulator of signaling pathways and microRNAs in different types of cancersSemantic proximity Read ↗

MiR-1271 Inhibits Cell Growth in Prostate Cancer by Targeting ERGSemantic proximity Read ↗

Tazarotene-Induced Gene 1 (TIG1) Expression in Prostate Carcinomas and Its Relationship to TumorigenicitySemantic proximity Read ↗

Long non‐coding RNA PRRT3‐AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagySemantic proximity Read ↗

LINC00992 contributes to the oncogenic phenotypes in prostate cancer via targeting miR-3935 and augmenting GOLM1 expression.Semantic proximity Read ↗

Suppression of ANT2 by miR-137 Inhibits Prostate TumorigenesisSemantic proximity Read ↗

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer.Semantic proximity Read ↗

Multiple roles of RARRES1 in prostate cancer: Autophagy induction and angiogenesis inhibition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.