Article
The heterogeneity of early Parkinson's disease: a cluster analysis on newly diagnosed untreated patients.
PloS one - 1 Jan 2013
Erro Roberto, Vitale Carmine, Amboni Marianna, Picillo Marina, Moccia Marcello, Longo Katia, Santangelo Gabriella, De Rosa Anna, Allocca Roberto, Giordano Flavio, Orefice Giuseppe, De Michele Giuseppe, Santoro Lucio, Pellecchia Maria Teresa, Barone Paolo
Abstract excerpt
BACKGROUND: The variability in the clinical phenotype of Parkinson's disease seems to suggest the existence of several subtypes of the disease. To test this hypothesis we performed a cluster analysis using data assessing both motor and non-motor symptoms in a large cohort of newly diagnosed untreated PD patients. METHODS: We collected data on demographic, motor, and the whole complex of non-motor symptoms from...
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