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Article

Epstein-Barr virus induction of the Hedgehog signalling pathway imposes a stem cell phenotype on human epithelial cells.

The Journal of pathology - 1 Nov 2013

Port Rebecca J, Pinheiro-Maia Sonia, Hu Chunfang, Arrand John R, Wei Wenbin, Young Lawrence S, Dawson Christopher W

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is a cancer common in southern China and South East Asia that is causally linked to Epstein-Barr virus (EBV) infection. Here, we demonstrate that NPC displays frequent dysregulation of the Hedgehog (HH) pathway, a pathway implicated in the maintenance of stem cells,...

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Share to Cell Transformation, Viral
Share to Epstein-Barr Virus Nuclear Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpesvirus 4, Human

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Share to Nasopharyngeal Neoplasms

Share to Neoplastic Stem Cells

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Source

Identifiers

PMID: 23934731
DOI: 10.1002/path.4245

Genes

SHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23934731-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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