Article
Identification and comparative analyses of myocardial miRNAs involved in the fetal response to maternal obesity.
Physiological genomics - 1 Oct 2013
Maloyan Alina, Muralimanoharan Sribalasubashini, Huffman Steven, Cox Laura A, Nathanielsz Peter W, Myatt Leslie, Nijland Mark J
Abstract excerpt
Human and animal studies show that suboptimal intrauterine environments lead to fetal programming, predisposing offspring to disease in later life. Maternal obesity has been shown to program offspring for cardiovascular disease (CVD), diabetes, and obesity. MicroRNAs (miRNAs) are small, noncoding RNA molecules that act as key regulators of numerous cellular processes. Compelling evidence links miRNAs to the...
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