Article
Interplay Between Inflammation and Epigenetic Changes in Cancer.
Progress in molecular biology and translational science - 1 Jan 2016
Maiuri A R, O'Hagan H M
Abstract excerpt
Immune responses can suppress tumorigenesis, but also contribute to cancer initiation and progression suggesting a complex interaction between the immune system and cancer. Epigenetic alterations, which are heritable changes in gene expression without changes to the DNA sequence, also play a role in carcinogenesis through silencing expression of tumor suppressor genes and activating oncogenic signaling....
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