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Altered microRNA and Piwi-interacting RNA profiles in cumulus cells from patients with diminished ovarian reserve†

23 Jun 2017

Abstract excerpt

Diminished ovarian reserve (DOR) is defined as decreased number or quality of follicles and oocytes in a woman at childbearing age. It is estimated that up to 10% of women in the general population may suffer from DOR. This study aims to comprehensively characterize microRNA (miRNA) and Piwi-interacting RNA (piRNA) expression profiles in cumulus cells of DOR patients. Cumulus cells were collected from 20 women of...

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PMID: 28651359
DOI: 10.1093/biolre/iox062

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