Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention.

Medicine and science in sports and exercise - 1 Feb 2014

Peter Inga, Papandonatos George D, Belalcazar L Maria, Yang Yao, Erar Bahar, Jakicic John M, Unick Jessica L, Balasubramanyam Ashok, Lipkin Edward W, Delahanty Linda M, Wagenknecht Lynne E, Wing Rena R, McCaffery Jeanne M, Huggins Gordon S

Abstract excerpt

PURPOSE: Numerous prospective studies indicate that improved cardiorespiratory fitness reduces type 2 diabetes risk and delays disease progression. We hypothesized that genetic variants modify fitness response to an intensive lifestyle intervention (ILI) in the Action for Health in Diabetes (Look AHEAD) randomized clinical trial, aimed to detect whether ILI will reduce cardiovascular events in overweight/obese...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenergic beta-Antagonists
Share to Core Binding Factor Alpha 2 Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exercise Test

Share to Health Behavior

Share to Physical Exertion

Share to Physical Fitness

Share to Risk Reduction Behavior

Share to Tacrolimus Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23899896
DOI: 10.1249/MSS.0b013e3182a66155
PMCID: PMC4055466

Genes

FKBP7
MET
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention.PMID 23899896Read ↗

Lifestyle genomics and the metabolic syndrome: A review of genetic variants that influence response to diet and exercise interventions.Semantic proximity Read ↗

Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial.Semantic proximity Read ↗

Association of type 2 diabetes susceptibility loci with one-year weight loss in the look AHEAD clinical trial.Semantic proximity Read ↗

SNP-by-fitness and SNP-by-BMI interactions from seven candidate genes and incident hypertension after 20 years of follow-up: the CARDIA Fitness Study.Semantic proximity Read ↗

Exercise training, genetics and type 2 diabetes-related phenotypes.Semantic proximity Read ↗

Advances in exercise, fitness, and performance genomics in 2014.Semantic proximity Read ↗

Cardiorespiratory fitness, genetic susceptibility, inflammation and risk of incident type 2 diabetes: A population-based longitudinal study.Semantic proximity Read ↗

Advances in Exercise, Fitness, and Performance Genomics in 2015Semantic proximity Read ↗

Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study.Semantic proximity Read ↗

Investigating the influence of mtDNA and nuclear encoded mitochondrial variants on high intensity interval training outcomes.Semantic proximity Read ↗

Genetic Contribution of Cardiorespiratory Fitness in Morbidity and Mortality: A Prospective FinnGen and HUNT studySemantic proximity Read ↗

A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.