Article
Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study.
Journal of biomedical science - 13 May 2021
Williams Camilla J, Li Zhixiu, Harvey Nicholas, Lea Rodney A, Gurd Brendon J, Bonafiglia Jacob T, Papadimitriou Ioannis, Jacques Macsue, Croci Ilaria, Stensvold Dorthe, Wisloff Ulrik, Taylor Jenna L, Gajanand Trishan, Cox Emily R, Ramos Joyce S, Fassett Robert G, Little Jonathan P, Francois Monique E, Hearon Christopher M, Sarma Satyam, Janssen Sylvan L J E, Van Craenenbroeck Emeline M, Beckers Paul, Cornelissen Véronique A, Howden Erin J, Keating Shelley E, Yan Xu, Bishop David J, Bye Anja, Haupt Larisa M, Griffiths Lyn R, Ashton Kevin J, Brown Matthew A, Torquati Luciana, Eynon Nir, Coombes Jeff S
Abstract excerpt
BACKGROUND: Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is considerable inter-individual variability in the V̇O2peak response to the same dose of exercise. Understanding how genetic factors contribute to V̇O2peak training response may improve personalisation...
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