Article
Cannabinoids decrease the th17 inflammatory autoimmune phenotype.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology - 1 Dec 2013
Kozela Ewa, Juknat Ana, Kaushansky Nathali, Rimmerman Neta, Ben-Nun Avraham, Vogel Zvi
Abstract excerpt
Cannabinoids, the Cannabis constituents, are known to possess anti-inflammatory properties but the mechanisms involved are not understood. Here we show that the main psychoactive cannabinoid, Δ-9-tetrahydrocannabinol (THC), and the main nonpsychoactive cannabinoid, cannabidiol (CBD), markedly reduce the Th17 phenotype which is known to be increased in inflammatory autoimmune pathologies such as Multiple...
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