Article
Ethanol alters gene expression and cell organization during optic vesicle evagination.
Neuroscience - 10 Oct 2013
Santos-Ledo A, Cavodeassi F, Carreño H, Aijón J, Arévalo R
Abstract excerpt
Ethanol has been described as a teratogen in vertebrate development. During early stages of brain formation, ethanol affects the evagination of the optic vesicles, resulting in synophthalmia or cyclopia, phenotypes where the optic vesicles partially or totally fuse. The mechanisms by which ethanol affects the morphogenesis of the optic vesicles are however largely unknown. In this study we make use of in situ...
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