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Article

An IL6-correlated signature in serous epithelial ovarian cancer associates with growth factor response

26 Jul 2013

Abstract excerpt

BACKGROUND: Epithelial ovarian cancer (EOC) is one of the most lethal gynecological cancers; the majority of EOC is the serous histotype and diagnosed at advanced stage. IL6 is the cytokine that has been found most frequently associated with carcinogenesis and progression of serous EOCs. IL6 is a growth-promoting and anti-apoptotic factor, and high plasma levels of IL6 in advanced stage EOCs correlate with poor...

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PMID: 23889749
DOI: 10.1186/1471-2164-14-508

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