Article
Genotyping by genome reducing and sequencing for outbred animals.
PloS one - 1 Jan 2013
Chen Qiang, Ma Yufang, Yang Yumei, Chen Zhenliang, Liao Rongrong, Xie Xiaoxian, Wang Zhen, He Pengfei, Tu Yingying, Zhang Xiangzhe, Yang Changsuo, Yang Hongjie, Yu Fuqing, Zheng Youmin, Zhang Zhiwu, Wang Qishan, Pan Yuchun
Abstract excerpt
Next-generation sequencing (NGS) approaches are widely used in genome-wide genetic marker discovery and genotyping. However, current NGS approaches are not easy to apply to general outbred populations (human and some major farm animals) for SNP identification because of the high level of heterogeneity and phase ambiguity in the haplotype. Here, we reported a new method for SNP genotyping, called genotyping by...
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