Article
Response to peginterferon alfa-2a (40KD) in HBeAg-negative CHB: on-treatment kinetics of HBsAg serum levels vary by HBV genotype.
Journal of hepatology - 1 Dec 2013
Brunetto Maurizia R, Marcellin Patrick, Cherubini Beatrice, Yurdaydin Cihan, Farci Patrizia, Hadziyannis Stephanos J, Rothe Vivien, Regep Loredana, Bonino Ferruccio
Abstract excerpt
BACKGROUND & AIMS: We investigated whether HBV genotype influences on-treatment HBsAg kinetics and/or the end-of-treatment HBsAg levels associated with long-term virological response in HBeAg-negative chronic hepatitis B patients treated with peginterferon alfa-2a±lamivudine in the Phase III trial. METHODS: All patients (n=230) who participated in long-term follow-up were included according to the availability of...
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