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Article

Defining natural species of bacteria: clear-cut genomic boundaries revealed by a turning point in nucleotide sequence divergence.

BMC genomics - 18 Jul 2013

Tang Le, Li Yang, Deng Xia, Johnston Randal N, Liu Gui-Rong, Liu Shu-Lin

Abstract excerpt

BACKGROUND: Bacteria are currently classified into arbitrary species, but whether they actually exist as discrete natural species was unclear. To reveal genomic features that may unambiguously group bacteria into discrete genetic clusters, we carried out systematic genomic comparisons among representative bacteria. RESULTS: We found that bacteria of Salmonella formed tight phylogenetic clusters separated by...

Topics

Bacteria
DNA, Bacterial
Evolution, Molecular
Genetic Variation
Genomics
Nucleotides
Phylogeny
Recombination, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23865772
DOI: 10.1186/1471-2164-14-489
PMCID: PMC3751360

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