Article
Classification of glucose-6-phosphate dehydrogenase variants by multivariate statistical analysis.
Biomedica biochimica acta - 1 Jan 1990
Buckwitz D, Jacobasch G, Post A
Abstract excerpt
Using principal component analysis a two-dimensional presentation of kinetic parameters from various G6PD-variants was obtained from which similarities between individual enzymes became detectable. Conclusions could be drawn as to how far the kinetic parameters contribute to the discrimination between different variants. An objective classification of G6PD-variants was achieved by application of cluster analysis....
Topics
- Cluster Analysis
- Genetic Variation
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Kinetics
- Multivariate Analysis