Article
Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population.
Kidney international. Supplement - 1 Aug 2007
Maeda S, Osawa N, Hayashi T, Tsukada S, Kobayashi M, Kikkawa R
Abstract excerpt
Genetic susceptibility plays an important role in the pathogenesis of diabetic nephropathy and type II diabetes. To identify the genetic polymorphisms associated with diabetic nephropathy and type II diabetes, we performed a genome-wide association study using single-nucleotide polymorphisms as genetic markers. We also analyzed polymorphisms within the genes encoding for the renin-angiotensin system that were...
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