Article
The incidence of EGFR-activating mutations in bone metastases of lung adenocarcinoma.
Pathology oncology research : POR - 1 Jan 2014
Krawczyk Paweł, Nicoś Marcin, Ramlau Rodryg, Powrózek Tomasz, Wojas-Krawczyk Kamila, Sura Sylwia, Jarosz Bożena, Szumiło Justyna, Warda Edward, Mazurkiewicz Tomasz, Sawicki Marek, Milanowski Janusz
Abstract excerpt
Poor prognosis of lung adenocarcinoma is associated with early occurrence of distant metastases. This type of non-small-cell lung carcinoma more frequently involves EGFR gene abnormalities, which determine the efficacy of EGFR tyrosine kinase inhibitor therapies (EGFR TKIs). It is probable that g...
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