Article
EGFR activating mutations detected by different PCR techniques in Caucasian NSCLC patients with CNS metastases: short report.
Clinical & experimental metastasis - 1 Dec 2013
Kamila Wojas-Krawczyk, Michał Skroński, Paweł Krawczyk, Paulina Jaguś, Tomasz Kucharczyk, Bożena Jarosz, Radosław Mlak, Justyna Szumiło, Marek Sawicki, Trojanowski Tomasz, Janusz Milanowski, Joanna Chorostowska-Wynimko
Abstract excerpt
EGFR mutation testing has become an essential determination to decide treatment options for NSCLC. The mutation analysis is often conducted in samples with low percentage of tumour cells from primary tumour biopsies. There is very little evidence that samples from metastatic tissues are suitable for EGFR testing. We had evaluated the frequency of EGFR mutations with three highly sensitive PCR techniques in...
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