Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondria-targeting cyclometalated iridium(III)-PEG complexes with tunable photodynamic activity.

Biomaterials - 1 Oct 2013

Li Steve Po-Yam, Lau Chris Tsan-Shing, Louie Man-Wai, Lam Yun-Wah, Cheng Shuk Han, Lo Kenneth Kam-Wing

Abstract excerpt

We present a new class of phosphorescent cyclometalated iridium(III) polypyridine poly(ethylene glycol) (PEG) complexes [Ir(N(^)C)2(bpy-CONH-PEG)](PF6) (bpy-CONH-PEG = 4-(N-(2-(ω-methoxypoly-(1-oxapropyl))ethyl)aminocarbonyl)-4'-methyl-2,2'-bipyridine, number average molecular weight (Mn) = 5272.23, weight average molecular weight (Mw) = 5317.38, polydispersity index (PDI) = 1.009; HN(^)C = 2-phenylpyridine, Hppy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cisplatin
Share to Endocytosis
Share to Inhibitory Concentration 50

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to L-Lactate Dehydrogenase

Share to Photochemotherapy

Share to Polyethylene Glycols

Share to Spectrometry, Fluorescence

Share to Tissue Distribution

Source

Identifiers

PMID: 23849346
DOI: 10.1016/j.biomaterials.2013.06.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondria-targeting cyclometalated iridium(III)-PEG complexes with tunable photodynamic activity.PMID 23849346Read ↗

Cyclometalated iridium( <scp>iii</scp> ) complexes induce mitochondria-derived paraptotic cell death and inhibit tumor growth <i>in vivo</i>Semantic proximity Read ↗

Multifunctional AIE Iridium (III) Photosensitizer Nanoparticles for Two-Photon-Activated Imaging and Mitochondria Targeting Photodynamic TherapySemantic proximity Read ↗

Bis[Pyrrolyl Ru(II)] Triads: a New Class of Photosensitizers for Metal-Organic Photodynamic TherapySemantic proximity Read ↗

Engineered multifunctional nanoparticles for enhanced radiation therapy: three-in-one approach for cancer treatmentSemantic proximity Read ↗

Self-Assembly of Erlotinib-Platinum(II) Complexes for Epidermal Growth Factor Receptor-Targeted Photodynamic Therapy.Semantic proximity Read ↗

Applications of Boron cluster Supramolecular Frameworks as Metal-free Chemodynamic Therapy AgentsSemantic proximity Read ↗

BODIPY Dyes: A New Frontier in Cellular Imaging and Theragnostic ApplicationsSemantic proximity Read ↗

Polymeric Encapsulation of a Ruthenium Polypyridine Complex for Tumor Targeted 1- and 2-Photon Photodynamic TherapySemantic proximity Read ↗

Development of intelligent nanogels by gamma radiation as theranostic agents for diagnosis and therapy of cancerSemantic proximity Read ↗

Biodegradable Mesoporous Manganese Carbonate Nanocomposites for LED Light-Driven Cancer Therapy via Enhancing Photodynamic Therapy and Attenuating Survivin ExpressionSemantic proximity Read ↗

Biomarker discovery and biotherapeutics applications of photosynthetic light-harvesting and bioluminescence light-emitting chromophore-protein complexes in stem cell biology and regenerative medicine.Semantic proximity Read ↗

A PI polyamide-TPP conjugate targeting a mtDNA mutation induces cell death of cancer cells with the mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.