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Article

Toxic effects of cephalosporins with specific functional groups as indicated by zebrafish embryo toxicity testing.

Chemical research in toxicology - 19 Aug 2013

Zhang Jingpu, Qian Jianqin, Tong Junwei, Zhang Dousheng, Hu Changqin

Abstract excerpt

Cephalosporins, derivatives of 7-aminocephalosporanic acid (7-ACA), are potent antibacterial agents. The toxicity prediction of these compounds is of considerable importance in new drug development. Zebrafish embryo toxicity testing was thought to be suitable for evaluation of the toxic properties of cephalosporins. Here, five kinds of cephalosporins and their isomers were used for investigation of the toxic...

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PMID: 23848171
DOI: 10.1021/tx400089y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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