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T Cell Antifungal Immunity and the Role of C-Type Lectin Receptors

5 Dec 2019

Abstract excerpt

Fungi can cause disease in humans, from mucocutaneous to life-threatening systemic infections. Initiation of antifungal immunity involves fungal recognition by pattern recognition receptors such as C-type lectin receptors (CLRs). These germline-encoded receptors trigger a multitude of innate responses including phagocytosis, fungal killing, and antigen presentation which can also shape the development of adaptive...

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Share to Antifungal resistance and susceptibility
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PMID: 31813764
DOI: 10.1016/j.it.2019.11.007

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