The Interaction of Human Pathogenic Fungi With C-Type Lectin Receptors

Abstract excerpt

Fungi, usually present as commensals, are a major cause of opportunistic infections in immunocompromised patients. Such infections, if not diagnosed or treated properly, can prove fatal. However, in most cases healthy individuals are able to avert the fungal attacks by mounting proper anti-fungal immune responses. Among the pattern recognition receptors (PRRs), C-type lectin receptors (CLRs) are the major players...