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Article

Neisseria gonorrhoeae virulence factor NG1686 is a bifunctional M23B family metallopeptidase that influences resistance to hydrogen peroxide and colony morphology.

The Journal of biological chemistry - 30 Mar 2012

Stohl Elizabeth A, Chan Yolande A, Hackett Kathleen T, Kohler Petra L, Dillard Joseph P, Seifert H Steven

Abstract excerpt

Symptomatic gonococcal infection, caused exclusively by the human-specific pathogen Neisseria gonorrhoeae (the gonococcus), is characterized by the influx of polymorphonuclear leukocytes (PMNs) to the site of infection. Although PMNs possess a potent antimicrobial arsenal comprising both oxidative and non-oxidative killing mechanisms, gonococci survive this interaction, suggesting that the gonococcus has evolved...

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Identifiers

PMID: 22334697
DOI: 10.1074/jbc.M111.338830
PMCID: PMC3322868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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