Article
KRAS as prognostic biomarker in metastatic colorectal cancer patients treated with bevacizumab: a pooled analysis of 12 published trials.
Medical oncology (Northwood, London, England) - 1 Jan 2013
Petrelli Fausto, Coinu Andrea, Cabiddu Mary, Ghilardi Mara, Barni Sandro
Abstract excerpt
The significance of KRAS in advanced colorectal cancer (CRC) treated with bevacizumab (B) is not well understood. We conducted a systematic review and pooled analysis of published trials with the aim to assess the predictive and prognostic role of KRAS status in patients treated with B. We performed a systematic search of PubMed, EMBASE, Web of Science, and Cochrane Register of Controlled Trials. The primary...
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