Article
Determinants of survival in advanced non--small-cell lung cancer in the era of targeted therapies.
Clinical lung cancer - 1 Sept 2013
Bauml Joshua, Mick Rosemarie, Zhang Yu, Watt Christopher D, Vachani Anil, Aggarwal Charu, Evans Tracey, Langer Corey
Abstract excerpt
BACKGROUND: Molecular profiling of non-small-cell lung cancer (NSCLC) samples has a profound impact on choice of therapy. However, it is less clear whether EGFR and KRAS mutations are prognostic outside of a trial-based treatment paradigm. METHODS: We performed a retrospective chart review of 513 patients with NSCLC undergoing EGFR and KRAS mutational analysis at the Hospital of the University of Pennsylvania...
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