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Article

Structural Characterization of Cleaved, Soluble HIV-1 Envelope Glycoprotein Trimers

4 Jul 2013

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) infection is a significant global public health problem for which development of an effective prophylactic vaccine remains a high scientific priority. Many concepts for a vaccine are focused on induction of appropriate titers of broadly neutralizing antibodies (bNAbs) against the viral envelope (Env) glycoproteins gp120 and gp41, but no immunogen has yet accomplished...

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PMID: 23824817
DOI: 10.1128/jvi.01222-13

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