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Induced pluripotent stem (iPS) cells from human fetal stem cells (hFSCs)

1 Apr 2013

Abstract excerpt

INTRODUCTION: (1) Human embryonic stem (ES) cells are pluripotent but are difficult to be used for therapy because of immunological, oncological and ethical barriers. (2) Pluripotent cells exist in vivo, i.e., germ cells and epiblast cells but cannot be isolated without sacrificing the developing embryo. (3) Reprogramming to pluripotency is possible from adult cells using ectopic expression of OKSM and other...

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PMID: 23823661
DOI: 10.4161/org.25197

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