Article
Slug promoted vasculogenic mimicry in hepatocellular carcinoma.
Journal of cellular and molecular medicine - 1 Aug 2013
Sun Dan, Sun Baocun, Liu Tieju, Zhao Xiulan, Che Na, Gu Qiang, Dong Xueyi, Yao Zhi, Li Rui, Li Jing, Chi Jiadong, Sun Ran
Abstract excerpt
Vasculogenic mimicry (VM) refers to the unique capability of aggressive tumour cells to mimic the pattern of embryonic vasculogenic networks. Epithelial-mesenchymal transition (EMT) regulator slug have been implicated in the tumour invasion and metastasis of human hepatocellular carcinoma (HCC). However, the relationship between slug and VM formation is not clear. In the study, we demonstrated that slug...
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