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Article

Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development.

Disease models & mechanisms - 1 Sept 2013

Liu Leah Y, Fox Caroline S, North Trista E, Goessling Wolfram

Abstract excerpt

Genome-wide association studies (GWAS) have revealed numerous associations between many phenotypes and gene candidates. Frequently, however, further elucidation of gene function has not been achieved. A recent GWAS identified 69 candidate genes associated with elevated liver enzyme concentrations, which are clinical markers of liver disease. To investigate the role of these genes in liver homeostasis, we narrowed...

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Identifiers

PMID: 23813869
DOI: 10.1242/dmm.011726
PMCID: PMC3759346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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