Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex regulation of autophagy in cancer - integrated approaches to discover the networks that hold a double-edged sword.

Seminars in cancer biology - 1 Aug 2013

Kubisch János, Türei Dénes, Földvári-Nagy László, Dunai Zsuzsanna A, Zsákai Lilian, Varga Máté, Vellai Tibor, Csermely Péter, Korcsmáros Tamás

Abstract excerpt

Autophagy, a highly regulated self-degradation process of eukaryotic cells, is a context-dependent tumor-suppressing mechanism that can also promote tumor cell survival upon stress and treatment resistance. Because of this ambiguity, autophagy is considered as a double-edged sword in oncology, making anti-cancer therapeutic approaches highly challenging. In this review, we present how systems-level knowledge on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Autophagy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Autophagy in Disease and Therapy

Share to Disease Models, Animal

Share to Mutation

Share to Neoplasms

Share to Protein Interaction Maps

Share to Signal Transduction

Source

Identifiers

PMID: 23810837
DOI: 10.1016/j.semcancer.2013.06.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex regulation of autophagy in cancer - integrated approaches to discover the networks that hold a double-edged sword.PMID 23810837Read ↗

Autophagy Regulatory Network — A systems-level bioinformatics resource for studying the mechanism and regulation of autophagySemantic proximity Read ↗

Deciphering autophagy signaling in cancer: A paradigm shift from molecular classifications to clinical innovationsSemantic proximity Read ↗

A systems biology analysis of autophagy in cancer therapySemantic proximity Read ↗

AutophagyNet: High-resolution data source for the analysis of autophagy and its regulationSemantic proximity Read ↗

Autophagy signal transduction by ATG proteins: from hierarchies to networksSemantic proximity Read ↗

A curated census of autophagy-modulating proteins and small moleculesSemantic proximity Read ↗

Autophagy signaling in cancer and its potential as novel target to improve anticancer therapySemantic proximity Read ↗

A gene toolbox for monitoring autophagy transcriptionSemantic proximity Read ↗

Regulation Mechanisms and Signaling Pathways of AutophagySemantic proximity Read ↗

Core signaling pathways of survival/death in autophagy-related cancer networksSemantic proximity Read ↗

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulationSemantic proximity Read ↗

Autophagy regulation as a promising approach for improving cancer immunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.