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Autophagy signal transduction by ATG proteins: from hierarchies to networks

21 Sept 2015

Abstract excerpt

Autophagy represents an intracellular degradation process which is involved in both cellular homeostasis and disease settings. In the last two decades, the molecular machinery governing this process has been characterized in detail. To date, several key factors regulating this intracellular degradation process have been identified. The so-called autophagy-related (ATG) genes and proteins are central to this...

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PMID: 26390974
DOI: 10.1007/s00018-015-2034-8

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