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Article

The Unique Expression and Function of miR-424 in Human Placental Trophoblasts1

27 Jun 2013

Abstract excerpt

Placental hypoperfusion causes cellular hypoxia and is associated with fetal growth restriction and preeclampsia. In response to hypoxia, the repertoire of genes expressed in placental trophoblasts changes, which influences key cellular processes such as differentiation and fusion. Diverse miRNAs were recently found to modulate the cellular response to hypoxia. Here we show that miR-424, which was previously...

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PMID: 23803556
DOI: 10.1095/biolreprod.113.110049

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