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Article

MiR‐205 silences MED1 in hypoxic primary human trophoblasts

11 Jan 2010

Abstract excerpt

Acting through degradation of target mRNA or inhibition of translation, microRNAs (miRNAs) regulate development, differentiation, and cellular response to diverse cues. We analyzed changes in miRNA expression in human placental trophoblasts exposed to hypoxia, which may result from hypoperfusion and placental injury. Using an miRNA microarray screen, confirmed by Northern blot analysis, we defined a set of seven...

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PMID: 20065103
DOI: 10.1096/fj.09-149724

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