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Article

Epidermal growth factor receptor expression and KRAS and BRAF mutations: study of 39 sinonasal intestinal-type adenocarcinomas.

Human pathology - 1 Oct 2013

Projetti Fabrice, Durand Karine, Chaunavel Alain, Léobon Sophie, Lacorre Sylvain, Caire François, Bessède Jean-Pierre, Moreau Jean-Jacques, Coulibaly Béma, Labrousse François

Abstract excerpt

Sinonasal intestinal-type adenocarcinomas (ITACs) are uncommon tumors of poor prognosis defined by their similarities to colorectal adenocarcinomas. The involvement of the epidermal growth factor receptor (EGFR) pathway in colorectal adenocarcinoma oncogenesis is well established, and the same is expected to apply to ITACs. In a series of 39 ITACs, we investigated EGFR amplification and chromosome 7 polysomy by...

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Source

Identifiers

PMID: 23791006
DOI: 10.1016/j.humpath.2013.03.019

Genes

EGFR
BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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