Article
Philadelphia chromosome positive childhood acute lymphoblastic leukemia: clinical and cytogenetic characteristics and treatment outcome. A Pediatric Oncology Group study.
Blood - 1 Aug 1990
Crist W, Carroll A, Shuster J, Jackson J, Head D, Borowitz M, Behm F, Link M, Steuber P, Ragab A
Abstract excerpt
Among 3,638 children with acute lymphoblastic leukemia (ALL) entered on Pediatric Oncology Group (POG) protocols between June 1981 and April 1989, successful cytogenetic studies were available for 2,519, 58 (2.3%) of which had the Philadelphia (Ph) chromosome detected. Features associated with the presence of the Ph chromosome were high leukocyte count (median, 33 x 10(9)/L), older age median, 9.6 years), a...
Topics
- Asparaginase
- Child
- Child, Preschool
- Cohort Studies
- Cross-Sectional Studies
- Female
- Humans
- Immunoglobulin Fc Fragments
- Male
- Phenotype
- Philadelphia Chromosome