Article
Regulation of lipid droplet size and phospholipid composition by stearoyl-CoA desaturase.
Journal of lipid research - 1 Sept 2013
Shi Xun, Li Juan, Zou Xiaoju, Greggain Joel, Rødkær Steven V, Færgeman Nils J, Liang Bin, Watts Jennifer L
Abstract excerpt
Fatty acid desaturation regulates membrane function and fat storage in animals. To determine the contribution of stearoyl-CoA desaturase (SCD) activity on fat storage and development in the nematode Caenorhabditis elegans, we analyzed the lipid composition and lipid droplet size in the fat-6;fat-7 desaturase mutants independently and in combination with mutants disrupted in conserved lipid metabolic pathways. C....
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