Article
S100P expression is a novel prognostic factor in hepatocellular carcinoma and predicts survival in patients with high tumor stage or early recurrent tumors.
PloS one - 1 Jan 2013
Yuan Ray-Hwang, Chang Ko-Tung, Chen Yu-Ling, Hsu Hey-Chi, Lee Po-Huang, Lai Po-Lin, Jeng Yung-Ming
Abstract excerpt
The calcium-binding protein S100P is expressed in a variety of human cancer cells and is important in cancer cell growth and invasion. Using differential display, we found S100P is overexpressed in human hepatocellular carcinoma (HCC). We examined the expression of 305 unifocal, primary HCC tumors using immunohistochemistry. The S100P protein was expressed in 173 of the 305 (56.7%) HCC tumors. The expression of...
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