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Article

Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle.

Human molecular genetics - 1 Nov 2013

Klymiuk Nikolai, Blutke Andreas, Graf Alexander, Krause Sabine, Burkhardt Katinka, Wuensch Annegret, Krebs Stefan, Kessler Barbara, Zakhartchenko Valeri, Kurome Mayuko, Kemter Elisabeth, Nagashima Hiroshi, Schoser Benedikt, Herbach Nadja, Blum Helmut, Wanke Rüdiger, Aartsma-Rus Annemieke, Thirion Christian, Lochmüller Hanns, Walter Maggie C, Wolf Eckhard

Abstract excerpt

Duchenne muscular dystrophy (DMD) is caused by mutations in the X-linked dystrophin (DMD) gene. The absence of dystrophin protein leads to progressive muscle weakness and wasting, disability and death. To establish a tailored large animal model of DMD, we deleted DMD exon 52 in male pig cells by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscular Dystrophy, Animal

Share to Muscular Dystrophy, Duchenne

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Source

Identifiers

PMID: 23784375
DOI: 10.1093/hmg/ddt287

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23784375-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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