Article
[Study on influence of cigarette smoking on the mutagenicity of urine. II. Animal experimental model of passive smoking].
Hinyokika kiyo. Acta urologica Japonica - 1 Apr 1990
Kanaoka T, Miyakawa M, Yoshida O
Abstract excerpt
We developed a convenient animal experimental model to study the effects of passive smoking on urinary mutagenicity. Rats were individually placed into metabolic cages, and were exposed to a side-stream of cigarette smoke under specific conditions. Then 24-hour urine collections were performed. Mutagenicity was investigated by the Ames test using the Salmonella typhimurium strains TA98 and TA100. In strain TA98,...
Topics
- Animals
- Biotransformation
- Female
- Models, Biological
- Mutagenicity Tests
- Mutation
- Rats
- Rats, Inbred F344
- Smoking
- Tobacco Smoke Pollution